Formulation Scientist
To support our growing operations in Leiden (NL), we are seeking a full-time formulation scientist who is up for the challenge of designing and testing formulations for a steady stream of drug candidates across many disease areas. You will utilize your knowledge of pharmaceutical chemistry to optimize formulations for solvent capacity, release behaviour and chemical/physical stability, and will show tenacity and creativity to achieve the target product profile.
Responsibilities
- Design formulations for poorly water-soluble drugs and drug candidates using SeraNovo’s deep eutectic solvent formulation platform
- Conduct physicochemical characterisation and preformulation activities, such as salt screening, solubility profiling and stress stability testing
- Conduct formulation performance tests, with an emphasis on biorelevant dissolution and physical stability testing (polarized light microscopy, XRPD, DSC)
- Work closely with the analytical team to ensure accurate and timely analysis of samples for assay/purity via HPLC-UV or HPLC-MS
- Analyze and interpret the results of experimental studies and write reports for both corporate records, customers and contractors
- Ensure proper transfer of production processes to SeraNovo’s network of preferred suppliers
- Execute and troubleshoot standard protocols, develop and adapt new protocols and query literature to incorporate additional assays as needed
Qualifications
- PhD in chemistry, pharmaceutics, chemical engineering or related discipline
- Fluency in English (both written and spoken)
Additional skills / preferences
- Out-of-the-box thinker
- Formulation development experience obtained in an industrial environment
- Hands-on experience with in vitro dissolution testing, DSC, XRPD, DLS or laser diffraction
- Proficiency with experimental design software (e.g. Modde® or MiniTab®)
- The ideal candidate will have the ability and willingness to work in an end-to-end manner, meaning that he/she understands the customer’s needs, translates these into a target product profile, designs and runs experiments and characterisation tests, troubleshoots and reiterates as needed, and finally communicates the outcomes via presentations and written reports to internal and external stakeholders.
To apply, please send a motivation letter and CV to
Niall Hodgins, CEO