Formulation Development With SeraNovo's Cutting Edge Solutions


Insights from the Case Study of Glibenclamide

INTRODUCTION

 

Formulation scientists globally face a significant challenge due to the low aqueous solubility of many active pharmaceutical ingredients. While current solutions like amorphous solid dispersions, nanosuspensions, and particle size reduction are valuable, they come with limitations. 

 

SeraNovo introduces innovative approaches to formulation development through our proprietary platforms, like LiDES. Our methods simplify production compared to traditional techniques, offering exceptional solutions to this persistent challenge.

 

For this case study, our objective was to formulate glibenclamide using a lipid-based approach, with the aim of achieving comparable drug loading to an amorphous solid dispersion while enhancing bioavailability. 

To delve deeper into the results and conclusions, download the full case study.