CASE STUDY: High-payload liquid formulation for Itraconazole


Harnessing the potential of our deep eutectic solvent platform, we have designed a formulation that has 14-fold higher ITZ loading than the marketed solution

The antimycotic compound ITZ is extremely poorly water-soluble, which is mainly driven by its high lipophilicity. The ITZ concentration in the original oral solution is only 10 mg/ml. Developing a high-payload solubilised formulation is difficult, given ITZ's extremely low solubility in traditional excipients.

 

Download the case study to learn about our eutectic solvent technology platform, and how we designed a formulation that has a 14-fold higher ITZ loading than the marketed oral solution.

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