In a feasibility study, we primarily focus on designing a deep eutectic solvent in which the API is highly soluble and that is physically and chemically stable. Based on the physicochemical profile of the API, we select a subset of candidate excipients from our library and screen these for deep eutectic forming ability. When formulation concepts that meet these criteria have been identified, we optimise for dissolution performance by incorporating excipients that keep the API in solution after release from the formulation, such as surfactants and polymers.
The key deliverable of a feasibility study is a report with clear conclusions and recommendations for follow-up work. Small samples of prototype formulations to support further testing in your facilities can also be provided at this time.